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KMID : 1141720170050010009
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폐쇄성폐질환
2017 Volume.5 No. 1 p.9 ~ p.9
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Kang Dae-Ryong
Park Joo-Hun
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Abstract
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The National Lung Cancer Trial (NLST) provided the evidence on the efficacy of lung cancer screening by low dose computed tomography (LDCT) to reduce the mortality of lung cancer. However, major trials conducted in Europe have not reproduced the favorable results of NLST trial. Meta-analysis including major trials reported that lung cancer screening by LDCT did not affect the overall mortality although lung cancer mortality was reduced, and uncertainty still exists concerning potential harms of screening such as false positive result, overdiagnosis, and radiation exposure. Therefore, further investigation about the efficacy of lung cancer screening by LDCT is necessary before broad clinical application.
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KEYWORD
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Lung cancer screening, Low dose computed tomography, Potential harms of screening
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