|
KMID : 1141720170050020006
|
|
폐쇄성폐질환
2017 Volume.5 No. 2 p.6 ~ p.6
|
|
|
|
|
Shin Su-Min
Lee Hyun
Park Hye-Yun
|
|
|
Abstract
|
|
|
Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms and airflow limitations with enhanced systemic inflammation. COPD is associated with numerous additional pulmonary and extrapulmonary manifestations, including the development of primary lung cancer. The risk of lung cancer in COPD patients is up to 5-fold higher than that in smokers without COPD, and lung cancer is a leading cause of death in patients with mild and moderate COPD. Furthermore, COPD patients are at an increased risk of pulmonary complications and poorer survival after lung cancer surgery compared with those without COPD. In particular, COPD patients with both moderate-to-severe airflow limitation and emphysema are at almost a 9-fold increased risk of postoperative pulmonary complications and poorer survival than patients with neither of these conditions. In lung cancer patients with untreated COPD, preoperative bronchodilator treatment may improve pulmonary function and the respiratory symptoms, enabling such patients to undergo curative lung resection and to exhibit fewer postoperative pulmonary complications. Integrated assessment of the severity of airflow limitation and emphysema status, and optimization of perioperative COPD management are essential to
minimize postoperative pulmonary complications developing after lung resection surgery.
|
|
|
KEYWORD
|
|
|
COPD, Emphysema, Lung cancer, Surgery, Postoperative Complication
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|