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KMID : 1141720190070010010
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폐쇄성폐질환
2019 Volume.7 No. 1 p.10 ~ p.14
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Song Woo-Jung
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Abstract
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Symptom is a defining component of asthma and makes direct impact on the patients' quality of life. However, in common instruments for asthma control, symptoms are just assessed in a simple non-specific way. In addition, most of clinical trials for asthma medications measure symptom scores using non-validated numeric scales. The disease paradigm of asthma is expanding, and now asthma is considered as a clinical syndrome encompassing various phenotypes and endotypes. Recently introduced concept of “treatable traits” suggests us to deconstruct the syndrome into several components such as genetic, biomarker, phenotypic or psychosocial parameters. Specific symptom including cough may be one of important treatable traits. Potential relevance of specific symptoms warrant further investigation in uncontrolled asthma.
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KEYWORD
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Asthma, Symptom, Cough, Control, Precision medicine
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