KMID : 1141720200080010012
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Æó¼â¼ºÆóÁúȯ 2020 Volume.8 No. 1 p.12 ~ p.16
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Does Earlier Intervention Have Better Outcomes in COPD?
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Kang Ji-Eun
Lee Jae-Seung
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Abstract
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Chronic obstructive pulmonary disease (COPD) is one of the major health problems worldwide and a treatment strategy to prevent or slow down disease progression is highly needed. This review discusses the current evidence for early intervention in COPD. Smoking cessation is the most effective intervention for altering the natural course of COPD. It has been shown to reduce the lung function decline rate as well as mortality. On the contrary, no studies have confirmed the same effect with pharmacotherapy. Few post-hoc and subgroup analyses showed potential benefits of bronchodilator treatment, but only limited evidence exists. Further studies are required to advocate early pharmacotherapy in COPD.
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KEYWORD
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COPD, Early intervention, Smoking cessation, Bronchodilator
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