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KMID : 1141720210090020053
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2021 Volume.9 No. 2 p.53 ~ p.58
Lee Sei-Won

Abstract
The recent development of biologics has dramatically improved the treatment of severe asthma, but the reality is that patients who are not adapted to biological agents such as T2 low asthma still do not have good treatment. Bronchoplasty mainly aims to reduce the volume of bronchial smooth muscle by applying heat to the bronchus, and demonstrates its effectiveness and safety through three representative clinical studies: AIR, AIR2, and RISA. However, extensive clinical application have yet to be recommended, due to limited indication, transient post-treatment acute exacerbations and no improvement in FEV1. Although further clinical research may be needed, thermoplasty can be considered for severe asthma with recurrent exacerbation who has no other treatment.
KEYWORD
Severe asthma, Bronchial thermoplasty, Acute exacerbation
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