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KMID : 1141720220100010021
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폐쇄성폐질환
2022 Volume.10 No. 1 p.21 ~ p.24
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Inhaled Corticosteroid (ICS) for Non-asthmatic Chronic Cough (Pro)
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Jeong In-A
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Abstract
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Chronic cough that persists beyond 8 weeks is a common clinical problem and causes considerable both physical and psychological morbidity. Currently, there are many international and domestic guidelines for chronic cough. They recommend a thorough history taking and physical exam when evaluating patients with chronic cough. If patients have a normal chest radiograph, major common causes and risk factors for chronic cough include asthma or cough variant asthma, upper airway cough syndrome, eosinophilic bronchitis and gastro-esophageal reflux disease. Pharmacologic treatment for chronic cough has limited efficacy resulting in decreased quality of life. It is well known that patients with asthma or eosinophilic bronchitis get improved their cough symptom with inhaled corticosteroid (ICS) treatment. What about the patients with non-asthmatic cough or unexplained chronic cough? While current guidelines recommend ICS, the research evidence for this intervention is conflicting.
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KEYWORD
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Chronic cough, Cough variant asthma, Non-asthmatic eosinophilic bronchitis, Inhaled corticosteroid
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