Chronic pulmonary obstructive disease (COPD) has been defined as a disease state characterized by airflow limitation that is not fully reversible. Traditionally, the airflow limitation is progressive and associated with an abnormal inflammatory response of the lungs to noxious particles or gases. The airflow limitation is also related to chronic inflammation of the airways and lungs. In terms of its progressive nature, early diagnosis could be the proper way to cope with COPD. Recently GOLD 2023 document revised the definition of COPD as “COPD is a heterogeneous lung condition characterized
by chronic respiratory symptoms (dyspnea, cough, sputum production) due to abnormalities of the airways (bronchitis, bronchiolitis) and alveoli (emphysema) that cause persistent, often progressive, airflow obstruction.” To eliminate COPD, it is necessary to expand the definition of COPD, reflecting heterogeneous causes and earlier pathologic changes.
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