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KMID : 1141720230110010037
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폐쇄성폐질환
2023 Volume.11 No. 1 p.37 ~ p.41
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BCO*: Severe Phenotype or Simple Comorbidity?
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Kim Seong-Yeol
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Abstract
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The development of bronchiectasis in patients with chronic obstructive pulmonary disease (COPD) and conversely, COPD in patients with bronchiectasis are recognized as significant clinical phenomenon. While COPD and bronchiectasis are distinct conditions, they can coexist and interact, leading to an increased burden of symptoms and potentially worse outcomes for affected individuals. The development of both disease in patients is thought to be multifactorial and can result from various mechanisms, including frequent respiratory infections, chronic airway inflammation, and impaired
mucociliary clearance. However, diagnosing bronchiectasis-COPD overlap can be challenging because they share similar symptoms and characteristics of both conditions. Therefore, a comprehensive evaluation and assessment are necessary, but there are lack of specific definitions and biomarkers to link COPD and bronchiectasis. A consensus for criteria defining radiological and clinical bronchiectasis in COPD patients is needed.
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KEYWORD
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chronic obstructive pulmonary disease, bronchiectasis, overlap, comorbidity
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