KMID : 1143520230110010107
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Journal of Korean Society of Oral Health Science 2023 Volume.11 No. 1 p.107 ~ p.113
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Antibacterial Activity of Lemongrass Oil and Lemongrass Ethanol Extract Against Porphyromonas gingivalis
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Yoon Hyun-Seo
Park Chung-Mu
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Abstract
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Objectives: This study analyzed the antibacterial effects of LGEE and LGEO against P. gingivalis, thus the potential utility was evaluated as the functional materials for oral healthcare.
Methods: Nitric oxide (NO) assay and cytotoxicity were analyzed by the Griess reaction and WST-1 assay, respectively. Antibacterial activity against P. gingivalis was evaluated by disk diffusion method and proliferation inhibition assay.
Results: LGEO and LGEE significantly inhibited NO production as well as the proliferation of P. gingivalis in a dose dependent manner.
Conclusions: LGEO and LGEE inhibited potently NO production and P. gingivalis proliferation, which means they could be used as a numerous lines of functional materials for improving oral health.
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KEYWORD
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Antibacterial, Lemon grass oil, Natural extracts, P.gingivalis
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