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KMID : 1144320190510020188
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감염과 화학요법
2019 Volume.51 No. 2 p.188 ~ p.190
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Validation of the Uniform Case Definition Criteria for Differentiating Tuberculous Meningitis, Viral Meningitis, and Bacterial Meningitis in Adults
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Kim Min-Chul
Park Ki-Ho
Lee Sang-Ahm
Kim Sung-Han
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Abstract
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We validated the uniform case definition for differentiating tuberculous meningitis (TBM) from both viral meningitis (VM) and bacterial meningitis (BM) in adults from South Korea, a country with an intermediate TB-burden. ‘Probable’ TBM differentiated ‘definite’ TBM with a sensitivity of 81% and specificity of 98%. ‘Possible TBM’ criteria identified ‘definite’ TBM with a sensitivity of 100% and specificity of 60%. Despite the usefulness of the uniform case definition criteria, there was substantial overlaps among VM, BM, and ‘possible’ TBM, especially in severe cases of VM and indolent cases of BM.
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KEYWORD
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Tuberculous meningitis, The uniform tuberculous meningitis case definition, Differentiation, Viral meningitis, Bacterial meningitis
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