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KMID : 1147920200030020047
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Medical Biological Science and Engineering
2020 Volume.3 No. 2 p.47 ~ p.51
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Opioid-induced hyperalgesia after implantation of intrathecal morphine pump: a case report
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Yoon Sung-Ryul
Choi Rak-Min
Lee Jae-Do
Won Jong-Chan
Lee Bou-Sung
Lee Kwang-Haeng
Kim Dong-Seok
Yang Jae-Young
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Abstract
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Opioid-induced hyperalgesia is characterized by an increased pain response to noxious stimuli despite increased use of opioid medications. Here, we report the case of a 43-year-old woman diagnosed with post-laminectomy syndrome who presented with an increasing pain score following a morphine infusion via an implanted intrathecal drug delivery device. Her pain improved after reducing opioid doses and the administration of intravenous ketamine infusion therapy. Thus, the early suspicion of opioid-induced hyperalgesia is essential for patients with increasing pain refractory to augmented doses of opioid medications.
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KEYWORD
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Hyperalgesia, Implantable, Intrathecal, Ketamine, Morphine, Opioid
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