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KMID : 1147920240070010040
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Medical Biological Science and Engineering
2024 Volume.7 No. 1 p.40 ~ p.46
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Rhabdomyolysis-induced acute kidney injury requiring hemodialysis in a patient on long-term, moderate-intensity rosuvastatin: a case report and literature review
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Lee So-Young
Kim Su-Yeon
Shin Jong-Ho
Kim Kyeong-Min
Lee Su-A
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Abstract
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Statins are widely used to prevent cardiovascular diseases. However, rhabdomyolysis is a well known adverse effect of statin use. The present report highlights a case of rhabdomyolysis-in duced acute kidney injury (AKI) in a patient receiving long-term moderate-intensity rosuvastatin.
Muscle weakness occurred 3 years after rosuvastatin administration. Myopathy and acute kidney injury resolved completely after withdrawal. To our knowledge, there have been no previously reported cases of moderate-intensity rosuvastatin-induced rhabdomyolysis-induced severe AKI requiring renal replacement therapy. This case report shows that moderate-intensity rosuvasta tin therapy is also associated with risk of severe rhabdomyolysis.
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KEYWORD
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Rhabdomyolysis, Acute kidney injury, Rosuvastatin
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