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KMID : 1148020130380010049
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2013 Volume.38 No. 1 p.49 ~ p.53
A Case of Sequential Hodgkin¡¯s Lymphoma following Successful Treatment of Non-Hodgkin¡¯s Lymphoma
Lee Hee-Jeong

Kim Hyung-Ho
Seo Jun-Won
Park Hyun-Jung
Park Sang-Gon
Abstract
Development of two different histologic types of lymphoma in the same person is rare. Sequential lymphoma is defined astwo different types of lymphoma occurring sequentially in the same person. In particular, sequential Hodgkin¡¯s lymphoma(HL) following non-Hodgkin¡¯s lymphoma (NHL) is extremely rare. A 63-year-old female diagnosed with B-cell NHL at themass in T3 received treatment with an R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone)protocol for six cycles. However, 12 months later, the patient complained of a left neck mass and excisional biopsy was performed.Microscopically the biopsied tissue showed Reed-Stemberg cells and confirmed the diagnosis of HL. The patientwas treated with ABVD (adriamycin, bleomycin, vinblastine and dacarbazine) for four cycles. Although the possibility of asecondary malignancy cannot be excluded, this is a rare case of sequential Hodgkin¡¯s lymphoma following Non-Hodgkin¡¯slymphoma.
KEYWORD
Sequential lymphoma , Hodgkin¡¯s lymphoma, Non-Hodgkin's lymphoma
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