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KMID : 1148020130380030114
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조선대학교의대논문집
2013 Volume.38 No. 3 p.114 ~ p.119
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The Metabolic Changes in F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography within One Month after Radiation Therapy of Cervix Cancer; Comparison with Magnetic Resonance Imaging
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Chong A-Ri
Ha Jung-Min
Song Ho-Chun
Jung Min-Young
Kim Young-Cheol
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Abstract
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We compared the results of early follow-up of F-18 FDG PET/CT and MRI performed within one month after radiationtherapy for cervix cancer patients. We conducted a retrospective review of the clinical data of cervix cancer patients whosePET/CT and pelvic MRI performed at staging and within one month from the end of RTx. SUVmax on PET/CT and size onMRI of the primary tumor were analyzed. We compared %change of SUVmax and size between staging and follow-up. Atotal of 27 patients were enrolled. At staging, larger tumor showed high SUVmax. At follow-up, no significant correlationwas observed between size and SUVmax. In 77.8% of patients, changes in SUVmax were well correlated with changes insize. No correlation was observed between % change and value at staging in both SUVmax and size. Except for six patientswho showed significant FDG uptake without evidence of a mass on MRI, % changes of size and SUVmax were well correlated.Metabolic change can be accessible on early follow-up PET/CT at±1 month from the end of the RTx of cervix cancer.However, careful interpretation of PET/CT is needed due to possible radiation-induced hypermetabolism even without adefinite mass on MRI.
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KEYWORD
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Cervix cancer, Fluorodeoxyglucose F18, Positron-emission tomography and computed tomography, Radiation therapy
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