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KMID : 1148020140390030120
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조선대학교의대논문집
2014 Volume.39 No. 3 p.120 ~ p.125
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Treatment Efficacy of Tenofovir in Korean Patients with Chronic Hepatitis B after Twelve Months of Treatment
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Ju Jong-Seok
Kang Sung-Hoon
Kim Seok-Won
Shin Hae-Jin
Lee Eaum-Seok
Kim Seok-Hyun
Lee Byung-Seok
Lee Heon-Young
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Abstract
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The aim of this study was to evaluate the efficacy of tenofovir in HBV patients at 12 months after treatment. A total of 122
chronic hepatitis B patients who took tenofovir for at least 12 months were enrolled. We measured ALT levels, HBeAg, anti-
HBe, HBV DNA, and serum creatinine at six and 12 months after treatment. The virological response rate at six and 12
months after treatment in naive patients was 27.1% and 41.7%, respectively. High virological response rate at six and 12
months after treatment showed an association with initial low HBV DNA titer and initial negative HBeAg status.
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KEYWORD
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Chronic Hepatitis B, Tenofovir
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