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KMID : 1148020140390030188
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조선대학교의대논문집
2014 Volume.39 No. 3 p.188 ~ p.192
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Sulfasalazine-induced Peripheral and Pleural Fluid Eosinophilia in Patient with Ankylosing Spondylitis
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Huh Jae-Hyung
Jo Won-Yong
Hong Jong-Min
Kim Ji-Eun
Suh Young-Sun
Lee Sang-Il
Kim Hyun-Ok
Nam Dae-Cheol
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Abstract
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Ankylosing spondylitis (AS) is an inflammatory joint disease affecting the axial skeleton, peripheral joints, entheses, and
extra-articular site. Non-steroidal anti-inflammatory agents are the first line drugs for treatment of AS. Sulfasalazine is re- garded as the second line drug and is usually used on AS patients with concomitant peripheral arthritis. Sulfasalazine has
side effects, including liver toxicity, hematological abnormality, skin eruption, and other symptoms. However, eosinophilic
pleural effusion is rare. Thus, we report on a patient with peripheral eosinophilia and eosinophilic pleural effusion after taking sulfasalazine for treatment of AS.
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KEYWORD
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Ankylosing spondylitis, Sulfasalazine, Eosinophilic pleural effusion
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