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KMID : 1148020140390040237
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조선대학교의대논문집
2014 Volume.39 No. 4 p.237 ~ p.243
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tudy of Total IgE Level and Allergen Specific IgE in Children with Acute Urticaria
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Cho So-Yeo
Kim Eun-Young
Rho Young-Il
Moon Kyung-Rye
Park Yeong-Bong
Yang Eun-Seok
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Abstract
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Increased total IgE and eosinophil count levels are thought to provoke the occurrence of urticaria. The purpose of this study is to measure serum total IgE levels, specific IgE sensitization rates, and blood eosinophil count and to investigate the relationship between those factors. Among children who visited the Department of Pediatrics at Chosun University Hospital from January 2011 to December 2013, we retrospectively analyzed 63 patients with acute urticaria. Positive rates of the total serum IgE level, specific IgE, and blood eosinophil count were analyzed in patients with acute urticaria. A total of 63 patients were included in the study and the rate of males to females was 1: 0.8. Mean age of patients was 6.41±4.97 years (range 0-17 years). Among the subjects, 42.9% of patients showed an elevated serum total IgE and 63.5% of patients showed at least more than one allergen-specific IgE by MAST (multiple allergosorbent test). The mean number of allergens detected in positive patients was 2.42±2.56/patient. The serum total IgE and allergen specific IgE showed significant positive correlation (OR = 0.290, p=0.02). This study is meaningful as it revealed a positive correlation between serum total IgE and allergen specific IgE in urticaria patients.
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KEYWORD
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Allergen-specific IgE, Total IgE, Blood eosinophil, MAST (multiple allergosorbent test), Urticaria
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