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KMID : 1148020140390040306
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조선대학교의대논문집
2014 Volume.39 No. 4 p.306 ~ p.308
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Toxic Hepatitis with Liver Fibrosis in a 67-year-old Man Who took Fritillaria thunbergii Miquel
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Rah Young-Min
Moon Kyoung-Min
Kim Ahn-Na
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Abstract
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A 67-year-old man visited our hospital with anorexia and abdominal discomfort after taking herb for 3 months. Abdominal computed tomograpy showed splenomegaly. Blood test showed elevation of serum alanine aminotransferase level, thrombocytopenia, and there was no viral or autoimmune hepatitis. Liver biopsy showed comprehensive fibrotic changes and necrosis on liver parenchyma. He recovered within 1 week after stopping the herb. There was no disease recurrence for 1 year. No case of toxic hepatitis by taking Fritillaria thunbergii Miquel has been reported. Thus, this case proved for the first time that Fritillaria thunbergii Miquel could cause drug induced liver injury.
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KEYWORD
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Herbal medicine, Hepatitis, Drug induced liver injury, Liver fibrosis, Traditional medicine
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