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KMID : 1148020140390040313
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조선대학교의대논문집
2014 Volume.39 No. 4 p.313 ~ p.317
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Bucillamine-induced Nephropathy in a Patient with Rheumatoid Arhtritis
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Nam Kyoung-Min
Park Jang-Ho
Byun Sang-Hwan
Jo Young-Sun
Kim Hyun-Ju
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Abstract
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There are many known renal complications of rheumatoid arthritis. These complications can develop by the extraarticular aspect of rheumatoid arthritis or the use of disease modifying antirheumatic drugs or pain-killer. The most common renal disease induced by use of disease modifying antirheumatic drugs is membranous nephropathy. We report on a case of bucillamine induced nephropathy with prominent proteinuria and hypoalbuminemia. The renal biopsy result was stage I to II membranous nephropathy. After withdrawal of bucillamine the proteinuria improved and hypoalbuminemia recovered. Even in cases of accompanying prominent proteinuria and hypoalbuminemia, bucillamine nephropathy can be treated with withdrawal of bucillamine and immunosuppressant drugs are not required.
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KEYWORD
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Bucillamine, Nephropathy, Membranous nephropathy, Rheumatoid arthritis, Proteinuria
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