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KMID : 1148020150400010025
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조선대학교의대논문집
2015 Volume.40 No. 1 p.25 ~ p.28
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Toxic Hepatitis by Repetitive Administration of Albendazole in a Short Time
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Shin Hong-Shik
Kim Byeong-Gwan
Cho A-Young
Lee Seong-Hee
Yun So-Hee
Cho Yong-Keun
Lee Kwang-Min
Yoo Seol-Bong
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Abstract
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Albendazole is the most commonly used medication worldwide for parasitic infestation. Albendazole may induce side effects such as nausea, vomiting, abdominal discomfort, and headache, however hepatotoxicity is rare. A 37- yearold woman was admitted to the hospital due to headache. Her child had been repeatedly infected with enterobius vermicularis, therefore she took albendazole three times for prophylactic purposes. The patient was diagnosed with hepatotoxicity induced by Albendazole based on a history of drug use; clinical symptoms and laboratory tests improved after ceasing drug administration, with a Roussel Uclaf Causality Assessment Method (RUCAM) score of 12.
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KEYWORD
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Albendazole, Hepatotoxicity, History taking, Parasitic infestation
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