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KMID : 1148020180430020094
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조선대학교의대논문집
2018 Volume.43 No. 2 p.94 ~ p.101
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Influence of Acute Respiratory Virus Infection on Kawasaki Disease
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Lee Hwoa-Rang
Cho Chul-Jun
Kim Yong-Wook
Kim Kyoung-Sim
Kim Eun-Young
Kim Young
Jang Hae-In
Cho Hyoung-Min
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Abstract
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The aim of this study was to determine the effect of acute respiratory viral infection on Kawasaki disease. From July 2016 to June 2018, among the patients who underwent respiratory virus screening at the Kwangju Christian Hospital, those diagnosed 88 patients with Kawasaki disease were enrolled in this study. The effects of acute respiratory viral infection on Kawasaki disease were compared according to whether 2nd intravenous immunoglobulin (IVIG) treatment was administered or not, and whether coronary artery complications occurred. Respiratory virus was detected in 44 out of 88 patients. 2nd IVIG treatment rates were 16% (n=7) and 27% (n=12) in the virus positive group and the virus negative group, respectively (p>0.05). The incidence of coronary artery complications was 11% (n=5) and 25% (n=11) in the virus positive group and the virus negative group, respectively (p>0.05). There was no statistically significant correlation between the 2nd IVIG administration and coronary artery complications following the detection of respiratory virus in patients with Kawasaki disease. We think it is necessary to actively study the effects of acute respiratory viral infection on Kawasaki disease through largescale studies of multiple centers in the future.
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KEYWORD
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Kawasaki disease, Respiratory virus, IVIG, Coronary aneurysm, Complications
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