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KMID : 1148020210460020068
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조선대학교의대논문집
2021 Volume.46 No. 2 p.68 ~ p.71
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Cefazolin-induced thrombocytopenia in a patient with postherpetic neuralgia - a case report
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Jong Hwa-Song
Jeon Hye-Jin
Cho Soo-Yeon
Jung Ki-Tae
Lim Kyung-Joon
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Abstract
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Drug-induced thrombocytopenia is a common clinical condition in hospitalized patients and can be led to fatal bleeding complications. Numerous medications are known to cause throm-bocytopenia. Diagnosis of thrombocytopenia is often delayed by another potential diagnosis like infection, heparin exposure, and immunologic disorders. Drug-induced thrombocytopenia can be developed due to two reasons, mainly: immune-mediated (increased destruction of platelets) or bone marrow suppression (reduced formation of platelets). Cefazolin, a first-generation ceph-alosporin, is a commonly used antibiotic for the prophylaxis of surgical or procedural site infection and has known to cause thrombocytopenia. We present a case of an 83-year-old woman with postherpetic neuralgia who experienced acute thrombocytopenia after the administration of ce-fazolin.
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KEYWORD
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Allodynia, Cefazolin, Herpes zoster, Postherpetic neuralgia, Thrombocytopenia
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