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KMID : 1148020230480010001
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조선대학교의대논문집
2023 Volume.48 No. 1 p.1 ~ p.7
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Four cases of newborns diagnosed with cow’s milk protein allergy after changing to amino acid-based formula
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Kim Hyun-Jong
Yoo Myung-Hwan
Seo Hyun-Sung
Jang Hae-In
Cho Hyoung-Min
Kim Eun-Young
Kim Kyoung-Sim
Kim Yong-Wook
Nuha M. Alhazmi
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Abstract
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Cow’s milk protein allergy(CMPA) or cow’s milk protein-induced allergy is the most common food allergy in children. It has been reported to have a 2 to 3% prevalence in infants within one year of age, but the exact prevalence in newborns within one month of age has not yet been accurately reported. In children who have non-specific symptoms such as diarrhea, bloody stool, vomiting, and urticaria within a few weeks of exposure to milk protein, if the symptoms improve
when changing to a diet without milk protein, a milk allergy can be diagnosed without additional tests. The extensively hydrolyzed formula is generally recommended first as a diet with milk protein eliminated, but amino acid-based formula can be considered preferentially as milk allergy may recur due to residual immunologically active proteins in the extensively hydrolyzed formula. In this report, the authors report four cases of newborns diagnosed with CMPA after changing to amino acid-based formula.
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KEYWORD
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Amino acid-based formula, Cow’s milk protein hypersensitivity, Newborn
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