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KMID : 1148920090430040352
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Nuclear Medicine and Molecular Imaging
2009 Volume.43 No. 4 p.352 ~ p.356
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Diffuse Bone Marrow Uptake of 99mTc-MIBI in A Case of Intravascular Large B-cell Lymphoma
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Moon Seung-Hwan
Oh So-Won
Paeng Jin-Chul
Paik Jin-Ho
Lee Dong-Soo
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Abstract
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National University College of Medicine, Seoul, Korea Intravascular large B-cell lymphoma (IVLBCL) is a subtype of diffuse large cell lymphoma, characterized by proliferation of lymphoid cells in the intravascular space of various organs without causing a mass effect. Although 18F-FDG PET is a powerful imaging tool in lymphoma, the usefulness of 18F-FDG PET in the assessment of IVLBCL is still controversial. 99mTc-MIBI, a tumor imaging radiopharmaceutical with a different mechanism from that of 18F-FDG, has been reported to be also effective in lymphoma. However, there is nearly no report on the efficacy of 99mTc-MIBI in the assessment of IVLBCL. We present one case of IVLBCL that showed 99mTc-MIBI accumulation in the involved bone marrow as an incidental finding, which was discrepant from that of 18F-FDG PET.
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KEYWORD
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Intravascular large B-cell lymphoma, 99mTc-MIBI, 18F-FDG PET
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