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KMID : 1148920090430060565
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Nuclear Medicine and Molecular Imaging
2009 Volume.43 No. 6 p.565 ~ p.571
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The Clinical Utility of Rectal Gas Distension F-18 FDG PET/CT
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Kim Jin-Suk
Lim Seok-Tae
Jeong Young-Jin
Kim Dong-Wook
Jeong Hwan-Jeong
Sohn Myung-Hee
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Abstract
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Purpose: The aim of this study was to evaluate the clinical value of rectal gas distension F-18 FDG PET/CT imaging for the differentiation of the rectal focal uptake lesions.
Materials and Methods: Twenty four patients (M:F=11:13, Age 62.8±12.4 years) underwent rectal gas distension F-18 FDG PET/CT, prospectively: initial image at 50-60 min after the intravenous injection of F-18 FDG and rectal distension image after the infusion of air through the anus. Focally increased uptake lesions on initial images but disappeared on rectal distension images defined a physiological uptake. For the differential evaluation of persistent focal uptake lesions on rectal distension images, colonoscopy and histopathologic examination were performed.
Results: Among the 24 patients, 27 lesions of focal rectal uptake were detected on initial images of F-18 FDG PET/CT. Of these, 7 lesions were able to judge with physiological uptake because the focal increased uptake disappeared from rectal distension image. Remaining 3 lesions were non-rectal lesions (2 lesions: rectovesical space, 1 lesion: uterine myoma). Among 17 lesions which was showed persistent increased uptake in rectal distension image, 15 lesions were confirmed as the malignant tumor (SUVmax=15.9±6.8) and 2 lesions were confirmed as the benign lesions including adenoma and inflammatory disease.
Conclusion: The rectal distension F-18 FDG PET/CT imaging could be an important noninvasive method for the differentiation of malignant and benign focal rectal uptake lesions including physiologic uptake.
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KEYWORD
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Rectal distension image, F-18 FDG, PET/CT
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