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KMID : 1148920160500030255
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Nuclear Medicine and Molecular Imaging
2016 Volume.50 No. 3 p.255 ~ p.257
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Cowden Syndrome Detected by FDG PET/CT in an Endometrial Cancer Patient
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Kang Yun-Hee
Lee Hye-Kyung
Park Geon
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Abstract
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Cowden syndrome (CS) is a rare autosomal dominant disorder characterized by multiple hamartomas in various tissues and cancers (breast, thyroid, and endometrium). We report CS of the esophagus and gastrointestinal tract that was incidentally detected by positron emission tomography/computed tomography (PET/CT) at postoperative surveillance in an endometrial cancer patient. PET/CT showed mildly increased FDG uptake along the entire esophagus and stomach. Upper GI endoscopy and histologic examination revealed glycogenic acanthosis of the esophagus and several hundred gastric polyps. In our case, increased FDG uptake of the esophageal wall contributed to the diagnosis of CS.
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KEYWORD
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Cowden syndrome, Hamartoma syndrome, Multiple, Fluorodeoxyglucose F18, Positron emission tomography
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