|
KMID : 1148920160500030270
|
|
Nuclear Medicine and Molecular Imaging
2016 Volume.50 No. 3 p.270 ~ p.272
|
|
|
False-Positive Radioactive Iodine Uptake Mimicking Miliary Lung Metastases in a Patient Affected by Papillary Thyroid Cancer and IgA Deficiency
|
|
Demidowich Andrew Paul
Kundu Amartya
Reynolds James C.
Celi Francesco S.
|
|
|
Abstract
|
|
|
|
A 42-year-old female with immunoglobulin A deficiency and recurrent sinopulmonary infections underwent thyroidectomy for papillary thyroid cancer (PTC). Follow-up 123I scintigraphy demonstrated diffuse pulmonary uptake, suggesting metastatic disease. However, subsequent pathologic, biochemical and radiographic testing proved that she was in fact disease free, and the initial 123I pulmonary uptake was identified as a false positive. Inflammatory conditions may rarely cause iodine uptake in non-thyroidal tissues due to local retention, organification, and/or immunologic utilization. To avoid exposing patients to unnecessary treatments, it is critical for clinicians to recognize that comorbid pulmonary conditions may mimic metastatic PTC on radioiodine scintigraphy.
|
|
|
KEYWORD
|
|
|
Radionuclide imaging, Scintigraphy, Papillary thyroid carcinoma, False-positive reactions, IgA deficiency
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|