KMID : 1148920160500040362
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Nuclear Medicine and Molecular Imaging 2016 Volume.50 No. 4 p.362 ~ p.364
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(99m)Tc-MIBI Uptake in a Thyroid Adenoma with Diffuse Adipose Metaplasia
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Paone Gaetano
Mazzucchelli Luca Peloni Giuseppe Fasolini Fabrizio Giovanella Luca
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Abstract
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A 71-year-old female underwent a (99m)Tc-MIBI scan to characterize a cold nodule (30 mm) of the left thyroid lobe. The nodule showed diffuse uptake and retention of the radiotracer. After resection, histological examination demonstrated a microfollicular adenoma with diffuse white adipose metaplasia. Although mitochondria in brown adipose tissue have been widely studied, we have only a limited understanding of the relevance of mitochondria in white adipose tissue. Active mitochondria are present in white adipocytes, and this may account for the MIBI uptake, mimicking a hyperproliferation pattern, in our patient.
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KEYWORD
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Tc MIBI, Thyroid, Adenoma, Adipocyte, Metaplasia
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