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KMID : 1148920170510040371
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Nuclear Medicine and Molecular Imaging
2017 Volume.51 No. 4 p.371 ~ p.373
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Radiation-Induced Giant Cell Granuloma Mimicking Relapsed Hodgkin Lymphoma at FDG-PET/CT
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Adams Hugo J. A.
De Klerk John M. H.
Regelink Josien C.
Heggelman Ben G. F.
Dubois Stefan V.
Kwee Thomas C.
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Abstract
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A 22-year-old woman was diagnosed with intermediate risk stage II Hodgkin lymphoma and treated with three cycles of adriamycin, bleomycin, vinblastine, and dacarbazine (ABVD) followed by involved-field radiation therapy. A complete metabolic remission was achieved after two cycles of ABVD, which was maintained until three years after completion of treatment. Follow-up FDG-PET/CT four years after completion of treatment, however, showed a new FDG-avid (Deauville score of 4) lesion in the right scapula, suggesting relapsed disease. Computer tomography (CT)-guided biopsy of this lesion was performed and subsequent histological examination revealed a radiation-induced giant cell granuloma.
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KEYWORD
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Biopsy, FDG-PET/CT, Giant cell granuloma, Hodgkin lymphoma
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