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KMID : 1148920220560020096
Nuclear Medicine and Molecular Imaging
2022 Volume.56 No. 2 p.96 ~ p.101
A Bone Scan Is Valuable for Primary Staging of Newly Diagnosed Prostate Cancer in a Low-Resource Setting (Nigeria)
Orunmuyi Akintunde T.

Adebayo Sikiru A.
Ilesanmi Olayinka S.
Takure Augustine O.
Olapade-Olaopa E. Oluwabunmi
Abstract
Objective: There is a paucity of information on bone scanning for prostate cancer from low-resource countries. This study evaluated the role of bone scan in the primary staging of newly diagnosed prostate cancer in one such setting.

Methods: A retrospective analysis of 126 men with newly diagnosed prostate cancer undergoing an initial staging bone scan between January 2017 and December 2020 was carried out at a regional nuclear medicine center in Nigeria. Bone scan results were analyzed according to age, serum level of baseline prostate-specific antigen (PSA), and Gleason score. Equivocal scans and patients with no Gleason score or baseline PSA were excluded from the analysis. p?
Results: Of 111 patients (aged 38?84 years, median 66 years), who met the inclusion criteria, 26 (23%) men had evidence of bony metastases as shown by a positive bone scan. Higher PSA levels and Gleason scores were associated with an increased risk of a positive bone scan, p?
Conclusion: The role of bone scanning in staging newly diagnosed prostate cancer patients in Nigeria is consistent with global reports. Our study confirms that a bone scan finding is well associated with the risk classification using PSA and Gleason score in our population.
KEYWORD
Prostate cancer, Metastasis, Bone scan, PSA, Gleason score
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