Àá½Ã¸¸ ±â´Ù·Á ÁÖ¼¼¿ä. ·ÎµùÁßÀÔ´Ï´Ù.
KMID : 1148920220560020102
Nuclear Medicine and Molecular Imaging
2022 Volume.56 No. 2 p.102 ~ p.104
[68 Ga]Ga-PSMA-11 Small Bowel Uptake in Crohn¡¯s Disease: Revisiting the ¡°Non-specificity¡± of PSMA Ligands
Chandekar Kunal Ramesh

Tanigassalam Sindhu
Kavanal Anwin Joseph
Singh Harmandeep
Bhattacharya Anish
Mavuduru Ravimohan Suryanarayan
Abstract
The rapidly evolving clinical utility of prostate-specific membrane antigen (PSMA) PET/CT as an imaging modality for prostate cancer (PCa) has brought to the forefront a multitude of non-prostatic diseases also exhibiting PSMA radioligand uptake. We report a case of a 71-year-old male with PCa who underwent PSMA PET/CT for recurrence evaluation. The scan demonstrated [68 Ga]Ga-PSMA-11 uptake in the distal ileum. Retrospective enquiry revealed that the patient was a known case of Crohn¡¯s disease. This case highlights an uncommon finding of PSMA radioligand uptake in the distal small bowel (non-prostatic benign pathological uptake) in a patient with known Crohn¡¯s disease, which may be misinterpreted in the evaluation of PCa.
KEYWORD
Prostate-specific membrane antigen (PSMA), Prostate cancer, PET/CT, Inflammatory bowel disease (IBD), Crohn¡¯s disease
FullTexts / Linksout information
Listed journal information
ÇмúÁøÈïÀç´Ü(KCI) KoreaMed ´ëÇÑÀÇÇÐȸ ȸ¿ø