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KMID : 1148920220560060328
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Nuclear Medicine and Molecular Imaging
2022 Volume.56 No. 6 p.328 ~ p.330
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Extramedullary Hematopoiesis Visualized on FDG-PET/CT in a Patient with Beta-Thalassemia
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Dahlsgaard-Wallenius Sara E.
Juul-Jensen Karen
Nielsen Anne Lerberg
Hildebrandt Malene Grubbe
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Abstract
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Beta-thalassemia is an inherited blood disorder caused by reduced or absent synthesis of the beta chains of hemoglobin, resulting in decreased hemoglobin production. Symptoms depend on the type of beta-thalassemia ranging from no symptoms to severe illness. Ineffective erythropoiesis leads to a sequence of events responsible for bone marrow expansion, anemia, hemolysis, splenomegaly, increased iron absorption, and sometimes extramedullary hematopoiesis (EMH). We report an interesting case with EMH visualized on FDG-PET/CT and where FDG-PET/CT has also found the focus of a severe infection in a patient with beta-thalassemia.
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KEYWORD
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Thalassemia, Extramedullary Hematopoiesis, Fluoro-2-deoxyglucose, Positron Emission Tomography/computer Tomography
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