|
KMID : 1151620170020010038
|
|
Journal of Retina
2017 Volume.2 No. 1 p.38 ~ p.41
|
|
|
Choroidal Neovascularization after Multiple Evanescent White Dot Syndrome in a Patient with Pre-existing Pigment Epithelial Detachment
|
|
Um Tae-Woong
Lee Joo-Yong
|
|
|
Abstract
|
|
|
Purpose: To report a case of choroidal neovascularization (CNV) occurring after resolution of multiple evanescent white dot syndrome (MEWDS) in a patient with pre-existing pigment epithelial detachment.
Case summary: A 31-year-old woman with decreased vision in the right eye as her main complaint visited our clinic. Initial examination showed mild inflammation of the anterior chamber and disc swelling with multiple white dots on the fundus. Hyper-fluorescent spots on fluorescein angiography (FA) and hypo-fluorescent spots on indocyanine green angiography (ICGA) were observed. Optical coherence tomography (OCT) showed small pigment epithelial detachment (PED) at the macula, but there was no angiographic evidence of active CNV. She was diagnosed with MEWDS. After 1 month of treatment with an oral corticosteroid, the white dots completely disappeared. Two weeks later, she complained of a central scotoma in the same eye. OCT showed intraretinal and subretinal hemorrhages in the macula and subretinal fluid (SRF), with FA and ICGA showing a hyper-fluorescent spot on the fovea with leakage, findings compatible with active CNV. SRF did not resolve after six serial intravitreal injections of bevacizumab, half-fluence photodynamic therapy, and or serial intravitreal injections of aflibercept, but resolved completely after three serial intravitreal injections of ranibizumab.
Conclusions: Active CNV can occur after MEWDS resolution in patients with predisposing conditions. Close follow-up after MEWDS resolution may be needed to detect CNV, particularly in patients with macular abnormalities such as PED.
|
|
|
KEYWORD
|
|
|
Choroidal neovascularization, Multiple evanescent white dot syndrome (MEWDS)
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|