KMID : 1151620170020020076
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Journal of Retina 2017 Volume.2 No. 2 p.76 ~ p.82
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Changes in Choroidal Thickness after Hemodialysis and the Influence of Diabetes
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Kang Hae-Min
Choi Jeong-Hoon Kim Seung-Jun Moon Sung-Jin Kim Chan-Ho
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Abstract
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Purpose: To evaluate the changes in subfoveal choroidal thickness (SFCT) after hemodialysis (HD) and to investigate the possible impact of diabetes mellitus (DM).
Methods: This prospective, interventional case series included 18 patients undergoing HD due to chronic renal failure. Mean SFCT was measured before (pre-HD) and after HD (post-HD), and the differences (¥ÄSFCT) were calculated for each eye. In addition, the ratio of SFCT change (%SFCT; ¥ÄSFCT/baseline SFCT ¡¿ 100, percent, %) was calculated.
Results: Ten patients (55.6%) had DM as the underlying etiology for HD. The mean SFCT was 311.8 ¡¾ 64.9 ¥ìm (177.5-468.0 ¥ìm) pre-HD and 311.2 ¡¾ 65.1 ¥ìm (191.5-454.5 ¥ìm) post-HD (p = 0.877). The mean ¥ÄSFCT was -4.4 ¡¾ 20.0 ¥ìm (-64.0 to 29.0 ¥ìm), and the mean %SFCT was 4.3 ¡¾ 4.4% (0 to 19.5%). The mean ¥ÄSFCT was significantly larger in patients with DM than those without DM (-14.1 ¡¾ 18.2 ¥ìm and 7.8 ¡¾ 15.6 ¥ìm; p = 0.006), but the mean %SFCT was not significantly different between the groups (4.4 ¡¾ 5.5% and 4.2 ¡¾ 2.6%; p = 0.315).
Conclusions: The mean SFCT was not significantly changed after HD. The change in mean SFCT was significantly larger in patients with DM than in those without.
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KEYWORD
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Choroid, Choroidal thickness, Diabetes mellitus, Hemodialysis
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