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KMID : 1151620170020020105
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Journal of Retina
2017 Volume.2 No. 2 p.105 ~ p.108
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Optic Neuropathy Associated with the Use of Phosphodiesterase-5 Inhibitors
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Moon In-Hee
Kang Hyun-Seung
Lee Sung-Chul
Kim Min
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Abstract
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Purpose: To report a case of optic neuropathy associated with the use of phosphodiesterase-5 inhibitors.
Case summary: A 60-year-old male with no significant medical history presented with a headache and blurry vision in his left eye that had persisted for 3 days. He had been diagnosed with headaches, which was likely due to the use of phosphodiesterase-5 inhibitors (PDE-5i). His blood pressure was normal, and his best-corrected visual acuity was 16/20 in both eyes. His color vision, pupil light reflex, and relative afferent pupillary defect tests were normal. The right-eye visual field examination showed no signs of abnormality, but the left-eye visual field showed an inferior horizontal scotoma. Fundus examination showed disc edema in both eyes and disc hemorrhage in the left eye, while optical coherence tomography showed subretinal fluid at the nasal side of the fovea in the left eye and disc edema in both eyes. PDE-5i were discontinued, and a steroid was prescribed. The edema resolved after 8 weeks of tapering. Based on this study, discontinuation of PDE-5i and low dose steroid use may be helpful for optic neuropathy recovery.
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KEYWORD
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Optic disc hemorrhage, Optic neuropathy, Phosphodiesterase-5 inhibitor, Sildenafil, Viagra
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