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KMID : 1151620190040010001
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Journal of Retina
2019 Volume.4 No. 1 p.1 ~ p.9
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Characteristics of Recurrence in Patients with Polypoidal Choroidal Vasculopathy and Myopic Choroidal Neovascularization
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Lim Hyung-Bin
Park Kee-Sup
Jo Young-Joon
Kim Jung-Yeul
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Abstract
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Purpose: To investigate the characteristics of recurrence in patients with polypoidal choroidal vasculopathy (PCV) and myopic choroidal neovascularization (CNV).
Methods: In total, 72 eyes from 70 patients with PCV and 51 eyes from 49 patients with myopic CNV were included. PCV and myopic CNV patients were followed up with a pro-re-nata regimen after three monthly injections of anti-vascular endothelial growth factor and underwent spectral-domain optical coherence tomography (SD-OCT). Changes in visual acuity and SD-OCT findings of macular lesions after recurrence were analyzed.
Results: We observed a significant difference in recurrence of PCV (59.7%) and myopic CNV (35.3%) during the follow-up period (p = 0.008). With the first recurrence, we observed higher levels of subretinal fluid (SRF) in patients with PCV (93.0%) than myopic CNV (22.2%; p < 0.001). In addition, we observed more subretinal hyperreflective lesions with blurred margins on SD-OCT for patients with myopic CNV (88.9%) than with PCV (18.6%; p < 0.001). Changes in central macular thickness (CMT) following recurrence were greater for patients in the PCV group than in the myopic CNV group (p = 0.024). However, visual acuity was lower in patients with myopic CNV than with PCV (p = 0.001).
Conclusions: We observed a greater number of new SRF than subretinal hemorrhage in patients with recurrent PCV, whereas a subretinal hyperreflective lesion with a blurred margin was a major finding in patients with myopic CNV. Myopic CNV patients experienced a greater decrease in visual acuity at recurrence than PCV patients despite minimal changes in CMT.
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KEYWORD
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Myopic choroidal neovascularization, Polypoidal choroidal vasculopathy, Optical coherence tomography, Recurrence
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