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KMID : 1151620190040010036
Journal of Retina
2019 Volume.4 No. 1 p.36 ~ p.39
Proliferative Retinopathy Developed in a Duchenne Muscular Dystrophy Patient with Normal Cardiac Function
Park Sun-Ho

Jo Yeon-Ji
Lee Jae-Jung
Park Sung-Who
Lee Ji-Eun
Abstract
Purpose: To report a case of severe proliferative retinopathy that developed in both eyes of a Duchenne muscular dystrophy (DMD) patient with normal cardiac function.

Case summary: A 30-year-old male patient with DMD was referred to our hospital due to decreased vision on both eyes. Best-corrected visual acuity (BCVA) was 20/1,000 in the right eye and finger counting in the left eye. Extensive retinal neovascularization with fibrovascular proliferation and dense vitreous hemorrhage was noted in both eyes. There was no cardiopulmonary insufficiency. Bevacizumab was injected as preoperative treatment 2 days prior to surgery; pars plana vitrectomy with laser photocoagulation and silicone oil injection was performed on both eyes. One month postoperatively, BCVA was 20/300 without subretinal fluid, and silicone oil was removed from both eyes. The retina remained attached without re-proliferation at the last follow-up, 18 months postoperatively.

Conclusions: Rapidly progressive bilateral proliferative retinopathy can occur in DMD patients without severe cardiopulmonary insufficiency. Considering its rapid progression, regular fundus examination and early intervention is recommended for proliferative retinopathy in DMD patients, for a better prognosis.
KEYWORD
Duchenne muscular dystrophy, Retinal diseases, Retinal neovascularization, Vitrectomy
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