KMID : 1151620200050020094
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Journal of Retina 2020 Volume.5 No. 2 p.94 ~ p.99
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Evaluation of the Safety of Bilateral Same-day Intravitreal Aflibercept Injections
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Ahn Ja-Young
Byun Zee-Yoon Jang Kyu-Hwan Sohn Joon-Hong Hwang Duck-Jin
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Abstract
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Purpose: To evaluate the safety of bilateral same-day intravitreal aflibercept injections by analyzing ophthalmic complications.
Methods: Medical records were retrospectively reviewed for patients who underwent bilateral same-day intravitreal aflibercept injections between January 2016 and December 2018. The patients visited 1 day, 1 week, 1 month, and 2 months after the injection.
Results: Same-day intravitreal aflibercept injections were administered to a total of 31 patients, including 62 eyes, 208 bilateral. The causes of injection were neovascular age-related macular degeneration in 192 (92.31%) injections and diabetic macular edema in 16 (7.69%) injections. None of the patients had endophthalmitis, vitreous hemorrhage or acute increase in intraocular pressure. Three (1.44%) eyes with acute intraocular inflammation were observed. Two eyes improved without any treatment. One eye showed 3+ cells in the anterior chamber 1 day after the injection, but the inflammation improved after 1 week of treatment. Four (1.92%) eyes had subconjunctival hemorrhage.
Conclusions: Bilateral same-day intravitreal aflibercept injections are safe, time-saving, and more economically favorable, which may reduce the burden on patients and physicians.
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KEYWORD
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Adverse effects, Aflibercept, Bilateral, Endophthalmitis, Safety
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