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KMID : 1151620210060010041
Journal of Retina
2021 Volume.6 No. 1 p.41 ~ p.47
Outcomes of Vitrectomy with Macular Membrane Peel in Eyes with Epiretinal Membrane and Coexisting Intermediate Stage Dry Age-related Macular Degeneration
Chae Sue-Hey

Lee Joo-Heon
Lee Min-Soo
Jeon Hey-Min
Yoon Hee-Seong
Abstract
Purpose: To evaluate the outcomes of pars plana vitrectomy with membrane peeling for intermediate stage dry age-related macular degeneration (AMD) coexisting epiretinal membrane and compare the result with the contralateral eye that has only intermediate stage dry AMD.

Methods: This retrospective, observational study comprised 41 patients diagnosed with epiretinal membrane treated with vitrectomy and membrane peeling for coexisting intermediate stage dry AMD. Changes in best-corrected visual acuity (BCVA) and central macular thickness (CMT) were studied by comparing the pre- and postoperative measurements. Thirty-four fellow eyes with intermediate stage dry AMD were compared as a control group. Preoperative and postoperative data of BCVA, CMT, development of choroidal neovascularization (CNV), and retinal atrophic change after the operation were evaluated.

Results: Surgical treatment resulted in a significant improvement in BCVA and decrease in CMT at postoperative 12 months. In the surgery group, there was 1 eye with CNV development and 1 eye with new central retinal atrophic change. In the control group, there was 1 eye with new central retinal atrophic change.

Conclusions: There was a significant improvement in visual acuity after vitrectomy and membrane peeling in eyes with intermediate stage dry AMD and epiretinal membrane. Future studies are needed to confirm the change of stage for dry AMD after surgical removal of the membrane.
KEYWORD
Choroidal neovascularization, Dry age-related macular degeneration, Epiretinal membrane
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