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KMID : 1151620210060020150
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Journal of Retina
2021 Volume.6 No. 2 p.150 ~ p.154
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Effect of High-dose Intravitreal Bevacizumab Injection on Refractory Idiopathic Choroidal Neovascularization
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Bang Jong-Wook
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Abstract
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Purpose: To report the effect of high-dose intravitreal bevacizumab injection on refractory idiopathic choroidal neovascularization.
Case summary: A 43-year-old male presented with vision loss in his right eye 7 days earlier. His best corrected visual acuity was counting fingers at 30 cm. In optical coherence tomography, macular edema, submacular hemorrhage, and subretinal fluid were observed; in FA, foveal leakage was observed. After three intravitreal ranibizumab injections and two intravitreal aflibercept injections, his best corrected visual acuity was 20/800, and macular edema and subretinal fluid persisted. After switching to high-dose intravitreal bevacizumab injection, gradual improvement of best corrected visual acuity and macular structural recovery were observed. After 5 monthly high-dose intravitreal bevacizumab injections, his best corrected visual acuity was 20/125, and macular edema was decreased.
Conclusions: We can consider high-dose intravitreal bevacizumab injection in a refractory idiopathic choroidal neovascularization patient as a treatment option.
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KEYWORD
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Bevacizumab, Choroidal neovascularization, Macular edema, Ranibizumab, Subretinal fluid
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