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KMID : 1155820140090010009
Neurointervention
2014 Volume.9 No. 1 p.9 ~ p.20
High-Resolution MRI of Intracranial Atherosclerotic Disease
Ryu Chang-Woo

Kwak Hyo-Sung
Jahng Geon-Ho
Lee Han-Na
Abstract
Intracranial atherosclerotic disease (ICAD) causes up to 10% of all ischemic strokes, and the rate of recurrent vascular ischemic events is very high. Important predictors of vulnerability in atherosclerotic plaques include the degree of stenosis and the underlying plaque morphology. Vascular wall MRI can provide information about wall structures and atherosclerotic plaque components. High-resolution (HR)-MRI in ICAD poses a greater challenge in the neurologic fields, because a high in-plane resolution and a high signal-to-noise ratio are required for vessel wall imaging of ICAD. Until now, plaque imaging of ICAD has focused on assessing the presence of a plaque and evaluating the plaque load. Going forward, evaluation of plaque vulnerability through analysis of imaging characteristics will be a critical area of research. This review introduces the acquisition protocol for HR-MRI in ICAD and the current issues associated with imaging.
KEYWORD
Intracranial atherosclerotic disease, Atherosclerosis, Cerebral arteries, Magnetic resonance imaging (MRI), Vessel wall imaging
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