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KMID : 1155820210160020091
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Neurointervention
2021 Volume.16 No. 2 p.91 ~ p.110
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Factors Contributing to an Efficacious Endovascular Treatment for Acute Ischemic Stroke in Asian Population
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Lee Jin-Soo
Hwang Yang-Ha
Sohn Sung-Il
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Abstract
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Although randomized control trials about endovascular treatment (EVT) of emergent large vessel occlusion (LVO) have demonstrated the success of mechanical thrombectomy as the choice of treatment, a wide range of caveats remain unaddressed. Asian patients were rarely included in the trials, thereby raising the question of whether the treatment could be generalized. In addition, there remains a concern on the feasibility of the method with respect to its application against intracranial atherosclerosis (ICAS)-related LVO, frequently observed in the Asian population. It is important to include evidence on ICAS LVO from Asian countries in the future for a comprehensive understanding of LVO etiology. Besides the issues with EVT, prognostic concerns in diabetes patients, acute kidney injury following EVT, neuroprotective management against reperfusion injury, and other peri-EVT issues should be considered in clinical practice. In the current article, we present an in-depth review of the literature that revises information pertaining to such concerns.
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KEYWORD
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Cerebral infarction, Endovascular procedures, Intracranial atherosclerosis, Diabetes mellitus, Acute kidney injury, Reperfusion injury
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