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KMID : 1157520140100020074
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International Journal of Clinical Preventive Dentistry
2014 Volume.10 No. 2 p.74 ~ p.86
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Calcium Carbonate and Sodium Chloride for Preventing Dentin Hypersensitivity and Gum Diseases
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Park Yong-Duk
Ahn Hyo-Kwang
Kwon Ha-Jeong
Kim Chan-Ho
Chae Sang-Kyun
Kim Yoo-Jin
Kim Wang-Gi
Hwang Kyung-Suk
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Abstract
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Objective: The purpose of this study was to test the efficacy and safety of dentifrice containing sodium alginate, fine calcium carbonate and sodium chloride which has effects of reducing dental hypersensitivity and anti-inflammatory effects.
Methods: Human dentin specimens obtained from extracted molars were embedded with an acrylic resin and etched with citric acid. The Specimens were stored in phosphate buffered saline buffer before being brushed 1 minute only with test dentifrices. Samples were analyzed by scanning electron microscopy. In clinical tests, 41 Korean adults brushed with dis-tributed dentifrice for three month the run-in period of two weeks. The improvements were compared between control and experimental groups using mixtures with sodium alginate, calcium carbonate and sodium chloride in different concen-trations.
Results: The efficacy of dentin occlusion of dentin tubules rises as Na-alginate and calcium carbonate contents increase. The occlusion efficacy in the experimental dentifrice is 5 times better than the control. Over three-month period, the test group showed 64.4% improvements based on the initial value and 86.5% improvements compared to the control group in the re-duction of dentin hypersensitivity (p＜0.05). In the gingival index, the test group showed 38.1% improvements based on the initial value and 76.7% improvements compared to the control group (p＜0.05).
Conclusion: The ingredients of sodium alginate and calcium carbonate to reduce dentin hypersensitivity and sodium chlor-ide and cetylpyridinium chloride to prevent gingivitis were indeed effective in protecting sensitive gingival. No side effects were found throughout the whole body including the oral cavity of the subjects.
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KEYWORD
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dentifrices, hypersensitivity, sodium alginate, calcium carbonate, sodium chloride, cetylpyridinium
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