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KMID : 1160220090370010037
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Mycobiology
2009 Volume.37 No. 1 p.37 ~ p.42
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Comparative Effects of Oyster Mushrooms on Lipid Profile, Liver and Kidney Function in Hypercholesterolemic Rats
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Alam Nuhu
Amin Ruhul
Khan Asaduzzaman
Ara Ismot
Shim Mi-Ja
Lee Min-Woong
Lee U-Youn
Lee Tae-Soo
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Abstract
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Comparative effects of oyster mushrooms on plasma and fecal lipid profiles and on liver and kidney function were evaluatedin hyper and normocholesterolemic rats. Feeding of hypercholesterolemic rats a 5% powder of oyster mushrooms (Pleurotusostreatus, P. sajor-caju and P. florida) reduced the plasma total cholesterol level by 37%, 21% and 16%, respectively andreduced the triglyceride level by 45%, 24% and 14%, respectively. LDL/HDL ratio decreased by 64%, 45% and 41% forP. sajor-caju, P. ostreatus and P. florida fed rats, respectively. Mushroom feeding also reduced body weight in hypercholesterolemicrats. However, it had no adverse effect on plasma bilirubin, creatinin and urea nitrogen level. Mushroom feedingalso increased the total lipid and cholesterol excretion in the feces. The present study reveals that feeding of 5% oyster mushroompowder does not have detrimental effects on the liver and kidneys rather may provide health benefits for the cardiovascular-related complication by decreasing the atherogenic lipid profiles.
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KEYWORD
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Hypercholesterolemic rats, Lipid profile, Liver and kidney function, Oyster mushrooms
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