|
KMID : 1160220100380010046
|
|
Mycobiology
2010 Volume.38 No. 1 p.46 ~ p.51
|
|
|
The Anti-inflammatory Effects of Water Extract from Cordyceps militaris in Murine Macrophage
|
|
Jo Wol-Soon
Choi Yoo-Jin
Kim Hyoun-Ji
Lee Jae-Yun
Nam Byung-Hyouk
Lee Jae-Dong
Lee Sang-Wha
Seo Su-Yeong
Jeong Min-Ho
|
|
|
Abstract
|
|
|
|
The aim of this study was to determine the in vitro anti-inflammatory effect of hot water extract from Cordyceps militaris fruiting bodies (CMWE) on lipopolysaccharide (LPS)-stimulated nitric oxide (NO) production, tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) release in RAW 264.7 cells. The treatment of macrophages with various concentrations of hot CMWE significantly reduced LPS-induced production as well as NO, TNF-α and IL-6 secretion in a concentration-dependent manner. These results suggest that CMWE have potent inhibitory effects on the production of these inflammatory mediators.
|
|
|
KEYWORD
|
|
|
Anti-inflammatory activity, Cordyceps militaris, Lipopolysaccharide, Nitric oxide, Pro-inflammatory cytokines, RAW 264.7 cell
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|