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KMID : 1160220100380040328
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Mycobiology
2010 Volume.38 No. 4 p.328 ~ p.330
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In Vitro Antifungal Activity of Equol against Candida albicans
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Lee Jeong-Ah
Chee Hee-Youn
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Abstract
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In this study, we demonstrate that equol has fungicidal activities against Candida albicans. The minimum inhibitory and minimum fungicidal concentrations of equol against C. albicans were 516 and 1,032 μM, respectively. Two separate viability assays found that equol changed the integrity of the C. albicans cell membrane, possibly by formation of membrane lesions. Scanning electron microscopy demonstrated ultrastructural changes.
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KEYWORD
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Candida albicans, Equol, Fungicidal activities
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