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KMID : 1160619960010020203
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Preventive Nutrition and Food Science
1996 Volume.1 No. 2 p.203 ~ p.207
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Antimutagenic Compounds Indentified from Chloroform Fraction of Persimmon Leaves
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Moon Suk-Hee
Kim Jeong-Ok
Park Kun-Young
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Abstract
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Methanol extract of dried persimmon leaves was refractionated using hexane, chloroform, ethylacetate, n-butanol aqueous fractions. Among these chloroform fraction showed the highest inhibition rate on the mutagenicities of aflatoxin B₁(AFB₁) and 3,2' -dimethyl-4-amino-bipheny1(DMAB) in Salmonella typhimurium TA 100. Chloroform fraction was further fractionated into eight fractions by silica gel column chromatography and thin layer chromatography(TLC). The fraction 5 on TLC exhibited the highest antimutagenic activities in AFB₁and DMAB. 2,4-Decadienal, dihydro-4-methyl-2(3H)-furanone, hexanoic acid 1,4-bis(1-methy1 ethy1)benzene, heptanoic acid, phenol, octanoic acid, nonanoic acid and benzoic acid were tentatively identified from this antimutagenic fraction by GC-MS.
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KEYWORD
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persimmom leaves, antimutagenic compounds
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