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KMID : 1160619960010020234
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Preventive Nutrition and Food Science
1996 Volume.1 No. 2 p.234 ~ p.238
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The Effect of Vitamin B6 Deficiency and Age on Plasma Cholesterol Profile in Intensely Exercised Rats
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Cho Youn-Ok
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Abstract
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The purpose of this study was to determine whether vitamin B_6 deficiency and age affect the blood cholesterol profile in exercising rats. Fifty four rats were fed either a vitamin B_6 deficient diet(-B_6) or a control diet(+B_6) for 6 weeks, then subdivided into 3 groups: non-exercise group(NE), exercise and sacrifice group (ES), exercise and recuperation group(ER). ES group was exercised on treadmill(10^0, 0.5~0.8㎞/h) for 2 hours and sacrifice. ER group was recuperated three days with respective diet after exercise. At week 3 and 6, the level of plasma total cholesterol(TC), high density lipoprotein cholesterol(HDL-C) and low density lipoprotein cholesterol(LDL-C) were compared. In NE group, there was no difference in the levels of TC, HDL-C and LDL-C between +B_6 rats and -B_6 rats. The plasma levels of TC and LDL-C of 6 weeks were higher than those of 3 weeks and no difference in HDL-C between 3 weeks rats and 6 weeks rats. In ES group, there was also no difference in the levels of TC, HDL-C and LDL-C between +B_6 rats and -B_6 rats and there was no difference in TC, LDL-cholesterol between 3 weeks rats and 6 weeks rats. The level of HDL-C of 6 weeks was lower than that of 3 weeks rats. In ER group, there was no difference in the levels of TC and LDL-C not only between +B_6 rats and -B_6 rats but also between 3 weeks rats and 6 weeks rats. The level of HDL-C was lower in -B_6 rats than that in +B_6 rats and higher in 6 weeks rats than in 3 weeks rats. These results suggest that vitamin B_6 deficiency may affect the HDL-C during exercise and after recuperation. The desirable effect of exercise on plasma cholesterol profile is strengthened in adult age than young age.
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KEYWORD
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vitamin B6 defidiency, age, cholesterol profile, exercise
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Listed journal information
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