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KMID : 1160620060110040285
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Preventive Nutrition and Food Science
2006 Volume.11 No. 4 p.285 ~ p.288
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Anti-adipogenic Effects of Dongchimi Nano Juice in Mouse 3T3-L1 Adipocytes
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Kong Chang-Suk
Lee Sun-Hyun
Seo Jung-Ok
Park Kun-Young
Rhee Sook-Hee
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Abstract
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The anti-adipogenic effect of dongchimi nano juice prepared using a nano-filtering process was investigated by measuring leptin and glycerol levels and the expression of a peroxisome proliferator-activated receptor-γ (PPARγ) gene as indicators of lipid accumulation or lipolysis. Red pepper powder, seeds of red pepper, garlic, and ginger were added in the preparation of dongchimi. Dongchimi was fermented to reach the optimal fermentation period, followed by nano-filtration in the range of 0.0005～0.1 ㎛. The lactic acid bacteria of dongchimi nano juice were removed completely by a nano-filtering process. Treatment of dongchimi nano juice induced glycerol release in the 3T3-L1 adipocytes and decreased the mRNA expression level of PPARγ. These results suggested that dongchimi nano juice may enhance lipolysis and modulate adipogenesis in 3T3-L1 cells.
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KEYWORD
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dongchimi, nano-filtering process, 3T3-L1 adipocytes, PPARγ, anti-adipogenic effect
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