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KMID : 1160620090140010086
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Preventive Nutrition and Food Science
2009 Volume.14 No. 1 p.86 ~ p.89
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Free Radical Scavenging Activity of Butanol Fraction from the Fruit of Citrus junos
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Cho Eun-Ju
Li Li
Piao Xiang-Lan
Lee Sang-Hyun
Kim Hyun-Young
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Abstract
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In this study, we investigated the free radical [1,1-diphenyl-2-picrylhydrazyl (DPPH), hydroxyl radical (·OH) and superoxide anion (O2-)] scavenging activity of MeOH extract and 3 fractions of Citrus junos. Of the tested fractions, the BuOH fraction showed the strongest DPPH scavenging activity, showing the IC50 values of 63.4 mg/mL. Therefore, we continuously carried out DPPH, ·OH and O2- scavenging activity tests of BuOH fraction of Citrus junos. The BuOH fraction of Citrus junos inhibited DPPH radical to 97.5% at a concentration of 1000 mg/mL and the scavenging activities were increased concentration-dependently. In addition, BuOH fraction from Citrus junos also scavenged ·OH in a concentration dependent manner from 5 to 1000 mg/mL. Furthermore, BuOH fraction showed about 56% O2--scavengimg activity at 25 mg/mL concentration but, the scavenging activities were not enhanced in a dose dependent manner. The present results suggest that BuOH fraction of Citrus junos would have the protective potential from oxidative stress induced by free radicals.
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KEYWORD
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Citrus junos, free radical, hydroxyl radicals, superoxide anion
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